Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure

Rørth, R. et al. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20(2), pp. 240-247. (doi: 10.1002/ejhf.1046) (PMID:29148231)

Abstract

Background: Employment status at time of first heart failure (HF) hospitalization may be an indicator of both self-perceived and objective health status. In this study, we examined the association between employment status and the risk of all-cause mortality and recurrent HF hospitalization in a nationwide cohort of patients with HF. Methods and Results: We identified all patients of working age (18-60 years) with a first HF hospitalisation in the period 1997-2015 in Denmark, categorized according to whether or not they were part of the workforce at time of the index admission. The primary outcome was death from any cause and the secondary outcome was readmission for HF. Cumulative incidence curves, binomial regression and Cox regression models were used to assess outcomes. Of 25571 patients with a first hospitalization for HF, 15428 (60%) were part of the workforce at baseline. Patients in the workforce were significantly younger (53 vs. 55 years) more likely to be male (75% vs 64%) and less likely to have diabetes (13% vs 22%) and chronic obstructive pulmonary disease (5% vs 10%), all p-values <0.001. Not being part of the workforce was associated with a significantly higher risk of death (HR: 1.59 [95% CI 1.50–1.68]) and rehospitalisation for HF (HR: 1.09 [95% CI 1.05–1.14]), in analyses adjusted for age, sex, comorbidities, education level, calendar time, duration of first HF hospitalization. Conclusion: Not being part of the workforce at time of first HF hospitalization was independently associated with increased mortality and recurrent HF hospitalization.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Kristensen, Mr Soren Lund and Jhund, Professor Pardeep and Mogensen, Dr Ulrik and Petrie, Professor Mark and McMurray, Professor John and Kober, Professor Lars
• Authors: Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., and Kristensen, S. L.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
• Journal Name: European Journal of Heart Failure
• Publisher: Wiley
• ISSN: 1388-9842
• ISSN (Online): 1879-0844
• Published Online: 16 November 2017
• Copyright Holders: Copyright © 2017 The Authors and European Society of Cardiology
• First Published: First published in European Journal of Heart Failure 20(2):240-247
• Publisher Policy: Reproduced in accordance with the publisher copyright policy