Development of a mechanical scanning device with high-frequency ultrasound transducer for ultrasonic capsule endoscopy

Wang, X. et al. (2017) Development of a mechanical scanning device with high-frequency ultrasound transducer for ultrasonic capsule endoscopy. IEEE Transactions on Medical Imaging, 36(9), pp. 1922-1929. (doi:10.1109/TMI.2017.2699973) (PMID:28475050)

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Abstract

Wireless capsule endoscopy has opened a new era by enabling remote diagnostic assessment of the gastrointestinaltract in a painless procedure. Video capsule endoscopy is currently commercially available worldwide. However, it is limited to visualization of superficial tissue. Ultrasound (US) imaging is a complementary solution as it is capable of acquiring transmural information from the tissue wall. This paper presents a mechanical scanning device incorporating a high-frequency transducer specifically as a proof of concept for US capsule endoscopy (USCE), providing information that may usefully assist future research. A rotary solenoid-coil-based motor was employed to rotate the US transducer with sectional electronic control. A set of gears was used to convert the sectional rotation to circular rotation. A single-element focused US transducer with 39-MHz center frequency was used for high-resolution US imaging, connected to an imaging platform for pulse generation and image processing. Key parameters of US imaging for USCE applications were evaluated. Wire phantom imaging and tissue phantom imaging have been conducted to evaluate the performance of the proposed method. A porcine small intestine specimen was also used for imaging evaluation in vitro. Test results demonstrate that the proposed device and rotation mechanism are able to offer good image resolution ( ~60 μm) of the lumen wall, and they, therefore, offer a viable basis for the fabrication of a USCE device.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cochran, Professor Sandy and Seetohul, Dr Vipin
Authors: Wang, X., Seetohul, V., Chen, R., Zhang, Z., Qian, M., Shi, Z., Yang, G., Mu, P., Wang, C., Huang, Z., Zhou, Q., Zheng, H., Cochran, S., and Qiu, W.
College/School:College of Science and Engineering > School of Engineering
College of Science and Engineering > School of Engineering > Systems Power and Energy
Journal Name:IEEE Transactions on Medical Imaging
Publisher:IEEE
ISSN:0278-0062
ISSN (Online):1558-254X

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
615381Sonopill: minimally invasive gastrointestinal diagnosis and therapyDavid CummingEngineering and Physical Sciences Research Council (EPSRC)EP/K034537/1ENG - ENGINEERING ELECTRONICS & NANO ENG