Volokhov, D.V., Becker, D.J., Bergner, L.M. , Camus, M.S., Orton, R.J. , Chizhikov, V.E., Altizer, S.M. and Streicker, D.G. (2017) Novel hemotropic mycoplasmas are widespread and genetically diverse in vampire bats. Epidemiology and Infection, 145(15), pp. 3154-3167. (doi: 10.1017/S095026881700231X) (PMID:29061202)
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Abstract
Bats (Order: Chiroptera) have been widely studied as reservoir hosts for viruses of concern for human and animal health. However, whether bats are equally competent hosts of non-viral pathogens such as bacteria remains an important open question. Here, we surveyed blood and saliva samples of vampire bats from Peru and Belize for hemotropic Mycoplasma spp. (hemoplasmas), bacteria that can cause inapparent infection or anemia in hosts. 16S rRNA gene amplification of blood showed 67% (150/223) of common vampire bats (Desmodus rotundus) were infected by hemoplasmas. Sequencing of the 16S rRNA gene amplicons revealed three novel genotypes that were phylogenetically related but not identical to hemoplasmas described from other (non-vampire) bat species, rodents, humans, and non-human primates. Hemoplasma prevalence in vampire bats was highest in non-reproductive and young individuals, did not differ by country, and was relatively stable over time (i.e., endemic). Metagenomics from pooled D. rotundus saliva from Peru detected non-hemotropic Mycoplasma species and hemoplasma genotypes phylogenetically similar to those identified in blood, providing indirect evidence for potential direct transmission of hemoplasmas through biting or social contacts. This study demonstrates vampire bats host several novel hemoplasmas and sheds light on risk factors for infection and basic transmission routes. Given the high frequency of direct contacts that arise when vampire bats feed on humans, domestic animals, and wildlife, the potential of these bacteria to be transmitted between species should be investigated in future work.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Orton, Dr Richard and Streicker, Professor Daniel and Bergner, Dr Laura |
Authors: | Volokhov, D.V., Becker, D.J., Bergner, L.M., Camus, M.S., Orton, R.J., Chizhikov, V.E., Altizer, S.M., and Streicker, D.G. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Epidemiology and Infection |
Publisher: | Cambridge University Press |
ISSN: | 0950-2688 |
ISSN (Online): | 1469-4409 |
Published Online: | 24 October 2017 |
Copyright Holders: | Copyright © 2017 Cambridge University Press |
First Published: | First published in Epidemiology and Infection 145(15):3154-3167 |
Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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