A cluster randomised control trial of a multi-component weight management programme for adults with intellectual disabilities and obesity

Harris, L., Hankey, C., Jones, N., Pert, C., Murray, H., Tobin, J., Boyle, S. and Melville, C. (2017) A cluster randomised control trial of a multi-component weight management programme for adults with intellectual disabilities and obesity. British Journal of Nutrition, 118(3), pp. 229-240. (doi:10.1017/S0007114517001933) (PMID:28831953)

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Abstract

There have been few published controlled studies of multi-component weight management programmes that include an energy deficit diet (EDD), for adults with intellectual disabilities and obesity. The objective of this study was to conduct a single-blind, cluster randomised controlled trial comparing a multi-component weight management programme to a health education programme. Participants were randomised to either TAKE 5, which included an EDD or Waist Winners Too (WWToo), based on health education principles. Outcomes measured at baseline, 6 months (after a weight loss phase) and 12 months (after a 6-month weight maintenance phase), by a researcher blinded to treatment allocation, included: weight; BMI; waist circumference; physical activity; sedentary behaviour and health-related quality of life. The recruitment strategy was effective with fifty participants successfully recruited. Both programmes were acceptable to adults with intellectual disabilities, evidenced by high retention rates (90 %). Exploratory efficacy analysis revealed that at 12 months there was a trend for more participants in TAKE 5 (50·0 %) to achieve a clinically important weight loss of 5-10 %, in comparison to WWToo (20·8 %) (OR 3·76; 95 % CI 0·92, 15·30; 0·064). This study found that a multi-component weight management programme that included an EDD, is feasible and an acceptable approach to weight loss when tailored to meet the needs of adults with intellectual disabilities and obesity.

Item Type:Articles
Keywords:EDD, EQ-5D, European Quality of Life-5 dimensions, IPAQ-S, International Physical Activity Questionnaire-Short, QOL, WWToo, Waist Winners Too, energy deficit diet, quality of life, intellectual disabilities, obesity, TAKE 5, weight management.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Harris, Dr Leanne and Murray, Mrs Heather and Jones, Ms Nathalie and Hankey, Dr Catherine and Melville, Professor Craig
Authors: Harris, L., Hankey, C., Jones, N., Pert, C., Murray, H., Tobin, J., Boyle, S., and Melville, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:British Journal of Nutrition
Publisher:Cambridge University Press
ISSN:0007-1145
ISSN (Online):1475-2662
Published Online:23 August 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in British Journal of Nutrition 118(3):229-240
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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