Megaoesophagus secondary to acquired myasthenia gravis

Yam, P.S. , Shelton, G.D. and Simpson, J.W. (1996) Megaoesophagus secondary to acquired myasthenia gravis. Journal of Small Animal Practice, 37(4), pp. 179-183. (doi:10.1111/j.1748-5827.1996.tb01957.x) (PMID:8731405)

Full text not currently available from Enlighten.


Fifteen dogs with confirmed adult onset idiopathic megaoesophagus, in which no generalised muscle weakness was observed, were tested for the presence of acetylcholine receptor antibodies. Of these, six were found to have values greater than 0–6 nmol/litre, previously determined to be diagnostic of acquired myasthenia gravis. The mean serum titre value for these dogs was 5–59 nmol/litre (range 0–78 to 8–72 nmol/litre). It appears that a significant proportion of dogs presenting with megaoesophagus have myasthenia gravis and, if a prompt diagnosis and appropriate treatment can be instituted, clinical signs may improve.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Yam, Dr Philippa
Authors: Yam, P.S., Shelton, G.D., and Simpson, J.W.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Journal of Small Animal Practice
ISSN (Online):1748-5827

University Staff: Request a correction | Enlighten Editors: Update this record