Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

Abul-Haija, Y. M. , Scott, G. G., Sahoo, J. K., Tuttle, T. and Ulijn, R. (2017) Cooperative, ion-sensitive co-assembly of tripeptide hydrogels. Chemical Communications, 53(69), pp. 9562-9565. (doi: 10.1039/C7CC04796G) (PMID:28805225)

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Abstract

Peptide co-assembly is of interest for the development of functional supramolecular biomaterials. Herein, computational simulations were combined with experimental validation to aid the design and understanding of cooperative co-assembly of a structure-forming tripeptide (FFD) and a functional copper-binding tripeptide (GHK) leading to hydrogel formation in response to complexation with copper ions.

Item Type:Articles
Additional Information:Funding information: EPSRC EP/K000586/1 is an infrastructure project for the ARCHIE-WeSt High Performance Computer
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Abul-Haija, Yousef
Authors: Abul-Haija, Y. M., Scott, G. G., Sahoo, J. K., Tuttle, T., and Ulijn, R.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemical Communications
Publisher:Royal Society of Chemistry
ISSN:1359-7345
ISSN (Online):1364-548X
Published Online:07 August 2017
Copyright Holders:Copyright © 2017 Royal Society of Chemistry
First Published:First published in Chemical Communications 53(69):9562-9565
Publisher Policy:Reproduced under a Creative Commons License

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