An optically driven pump for microfluidics

Leach, J., Mushfique, H., di Leonardo, R., Padgett, M. and Cooper, J. (2006) An optically driven pump for microfluidics. Lab on a Chip, 6, pp. 735-739. (doi: 10.1039/b601886f)

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We demonstrate a method for generating flow within a microfluidic channel using an optically driven pump. The pump consists of two counter rotating birefringent vaterite particles trapped within a microfluidic channel and driven using optical tweezers. The transfer of spin angular momentum from a circularly polarised laser beam rotates the particles at up to 10 Hz. We show the that the pump is able to displace fluid in microchannels, with flow rates of up to 200 µm<sup>3</sup> s<sup>−1</sup> (200 fL s<sup>−1</sup>). The direction of fluid pumping can be reversed by altering the sense of the rotation of the vaterite beads. We also incorporate a novel optical sensing method, based upon an additional probe particle, trapped within separate optical tweezers, enabling us to map the magnitude and direction of fluid flow within the channel. The techniques described in the paper have potential to be extended to drive an integrated lab-on-chip device, where pumping, flow measurement and optical sensing could all be achieved by structuring a single laser beam.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Padgett, Professor Miles and Cooper, Professor Jonathan and Leach, Mr Jonathan
Authors: Leach, J., Mushfique, H., di Leonardo, R., Padgett, M., and Cooper, J.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
College of Science and Engineering > School of Physics and Astronomy
Journal Name:Lab on a Chip
Publisher:Royal Society of Chemistry
ISSN (Online):1473-0189
Published Online:28 April 2006

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
362881Micro-fluidic analytical systems driven and interrogated with holographic opticsMiles PadgettEngineering & Physical Sciences Research Council (EPSRC)GR/S73006/01P&A - PHYSICS & ASTRONOMY