Review: emerging concepts in the pathogenesis of tendinopathy

Dean, B. J.F., Dakin, S. G., Millar, N. L. and Carr, A. J. (2017) Review: emerging concepts in the pathogenesis of tendinopathy. Surgeon, 15(6), pp. 349-354. (doi: 10.1016/j.surge.2017.05.005) (PMID:28619548) (PMCID:PMC5714045)

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Tendinopathy is a common clinical problem and has a significant disease burden attached, not only in terms of health care costs, but also for patients directly in terms of time off work and impact upon quality of life. Controversy surrounds the pathogenesis of tendinopathy, however the recent systematic analysis of the evidence has demonstrated that many of the claims of an absence of inflammation in tendinopathy were more based around belief than robust scientific data. This review is a summary of the emerging research in this topical area, with a particular focus on the role of neuronal regulation and inflammation in tendinopathy.

Item Type:Articles
Keywords:Inflammation, pain, pathogenesis, tendinitis, tendinopathy, tendon.
Glasgow Author(s) Enlighten ID:Millar, Professor Neal
Authors: Dean, B. J.F., Dakin, S. G., Millar, N. L., and Carr, A. J.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Surgeon
Publisher:Royal College of Surgeons Edinburgh
ISSN (Online):1479-666X
Published Online:12 June 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Surgeon 15(6): 349-354
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
620681The role of microRNA 29 in tendon diseaseNeal MillarWellcome Trust (WELLCOTR)100651/Z/12/ZIII -IMMUNOLOGY