Mcaulay, K. and Clark, J. S. (2017) Total synthesis of 7-epi-pukalide and 7-acetylsinumaximol B. Chemistry: A European Journal, 23(41), pp. 9761-9765. (doi: 10.1002/chem.201702591)
|
Text
142128.pdf - Accepted Version 822kB |
Abstract
Convergent total syntheses of the furanocembranoids 7-epi-pukalide and 7-acetylsinumaximol B have been achieved using a one-pot Knoevenagel condensation and thioether-mediated furan-forming reaction. Furan formation proceeds via a sulfur ylide and results in rapid introduction of structural complexity during the coupling of two highly functionalised fragments. The target compounds have been prepared in 16 steps from (R)-perillyl alcohol.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Clark, Professor Stephen and Mcaulay, Kirsten |
| Authors: | Mcaulay, K., and Clark, J. S. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Chemistry: A European Journal |
| Publisher: | Wiley |
| ISSN: | 0947-6539 |
| ISSN (Online): | 1521-3765 |
| Published Online: | 08 June 2017 |
| Copyright Holders: | Copyright © 2017 Wiley-VCH Verlag |
| First Published: | First published in Chemistry: A European Journal 23(41):9761-9765 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
University Staff: Request a correction | Enlighten Editors: Update this record
Deposit and Record Details
Deposit and Record Details