Is adolescent alcohol use associated with self-reported hypomanic symptoms in adulthood? - Findings from a prospective birth cohort

Fasteau, M., Mackay, D. , Smith, D. J. and Meyer, T. D. (2017) Is adolescent alcohol use associated with self-reported hypomanic symptoms in adulthood? - Findings from a prospective birth cohort. Psychiatry Research, 255, pp. 232-237. (doi: 10.1016/j.psychres.2017.05.034) (PMID:28582719)

Abstract

High rates of alcohol use disorder (AUD) are reported in people with major depression (MD) and bipolar disorder (BD). Substance abuse problems in adolescence may also indicate risk for future onset of mood disorders, especially BD. Data collected from the Avon Longitudinal Study of Parents and Children (ALSPAC), a large UK birth cohort, allowed information to be collected over several different time points and to test whether problematic alcohol use at age 16 was predictive of vulnerability to hypomanic symptoms at age 23. Controlling for a participant's gender, SES, marital status of the mother, a likely history of maternal depression, and adolescents’ level of depressive symptoms at age 16, a hierarchical linear regression revealed that self-reported alcohol use in adolescence predicted the future onset of hypomanic/manic symptoms. Limitations include attrition and relying solely on self-ratings. Despite these limitations, the results suggest problematic alcohol use in adolescence predicts a vulnerability to hypomanic or manic symptoms.

• Item Type: Articles
• Additional Information: The UK Medical Research Council and the Wellcome Trust (Grant ref: 102215/2/13/2) and the University of Bristol provide core support for ALSPAC.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Smith, Professor Daniel and Mackay, Professor Daniel
• Authors: Fasteau, M., Mackay, D., Smith, D. J., and Meyer, T. D.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health
• Journal Name: Psychiatry Research
• Publisher: Elsevier
• ISSN: 0165-1781
• ISSN (Online): 1872-7123
• Published Online: 22 May 2017
• Copyright Holders: Copyright © 2017 Elsevier B.V.
• First Published: First published in Psychiatry Research 255:232-237
• Publisher Policy: Reproduced in accordance with the publisher copyright policy