Current approaches for modulation of the nanoscale interface in the regulation of cell behavior

Donnelly, H., Dalby, M. J. , Salmeron-Sanchez, M. and Sweeten, P. E. (2018) Current approaches for modulation of the nanoscale interface in the regulation of cell behavior. Nanomedicine: Nanotechnology, Biology and Medicine, 14(7), pp. 2455-2464. (doi: 10.1016/j.nano.2017.03.020) (PMID:28552647) (PMCID:PMC6173683)

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Abstract

Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the field of biomaterials research. In this review, we discuss relevant nanofabrication techniques and how they are combined with bioengineering applications to mimic the natural extracellular matrix (ECM) and create valuable nanoscale interfaces.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Salmeron-Sanchez, Professor Manuel and Dalby, Professor Matthew and SWEETEN, Paula and Donnelly, Dr Hannah
Authors: Donnelly, H., Dalby, M. J., Salmeron-Sanchez, M., and Sweeten, P. E.
College/School:College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
Journal Name:Nanomedicine: Nanotechnology, Biology and Medicine
Publisher:Elsevier
ISSN:1549-9634
ISSN (Online):1549-9642
Published Online:26 May 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Nanomedicine: Nanotechnology, Biology and Medicine 14(7): 2455-2464
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
600931Development of nanopatterned substrates for the delivery of high quality stem cellsNikolaj GadegaardBiotechnology and Biological Sciences Research Council (BBSRC)BB/K011235/1ENG - BIOMEDICAL ENGINEERING
608751Dynamic surfaces to mimic mesenchymal stem cell niche functionsMatthew DalbyBiotechnology and Biological Sciences Research Council (BBSRC)BB/K006908/1RI MOLECULAR CELL & SYSTEMS BIOLOGY
615571Multiscale topographical modulation of cells and bacteria for next generation orthopaedic implantsMatthew DalbyEngineering and Physical Sciences Research Council (EPSRC)EP/K034898/1RI MOLECULAR CELL & SYSTEMS BIOLOGY