Development and validation of a novel paediatric weight estimation equation in multinational cohorts of sick children

Mcvey, L., Young, D., Hulst, J., Bradley, S. , Raudaschl, A., Karagiozoglou, T., Macleod, I., Joosten, K., Spenceley, N. and Gerasimidis, K. (2017) Development and validation of a novel paediatric weight estimation equation in multinational cohorts of sick children. Resuscitation, 117, pp. 118-121. (doi: 10.1016/j.resuscitation.2017.04.025) (PMID:28465140)

Abstract

Aim: In sick children who are unable to be weighed estimation of weight is often required, but the routinely used equations lack accuracy and precision. This study aimed to develop a novel equation (Children’s European Estimator of Weight-CEEW) using measurements of mid-upper arm circumference (MUAC) and other predictors in multinational groups of sick children in Europe. Methods: Weight estimation equations were developed in 2086 children from the UK, Greece and the Netherlands, using a combination of demographics, MUAC and height measurements. The final CEEW equations were compared against the performance of the European Resuscitation Council (ERC), Advanced Paediatric Life Support (APLS) and the Cattermole equations. Results: Two final CEEW equations were developed, incorporating measurements of age, gender and MUAC, with (CEEW1) or without (CEEW2) the inclusion of height. Both equations presented very high coefficients of determination (R2 > 96.5%), minimal mean prediction error and narrower limits of agreement than the comparator equations. 88% (CEEW1) and 77% (CEEW2) of weight estimates fell within 15% of measured body weight. These figures compared with less than 57%, 57% and 37% for the ERC, APLS and Cattermole equations respectively. Conclusion: The CEEW equations performed substantially better than other routinely used equations for weight estimation. An electronic application for mobile use is presented.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Spenceley, Dr Neil and Gerasimidis, Professor Konstantinos and Bradley, Miss Sarah and Mcvey, Dr Lindsey
• Authors: Mcvey, L., Young, D., Hulst, J., Bradley, S., Raudaschl, A., Karagiozoglou, T., Macleod, I., Joosten, K., Spenceley, N., and Gerasimidis, K.
• College/School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Resuscitation
• Publisher: Elsevier
• ISSN: 0300-9572
• ISSN (Online): 1873-1570
• Published Online: 29 April 2017
• Copyright Holders: Copyright © 2017 Elsevier
• First Published: First published in Resuscitation 117:118-121
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher