Ray, D., Hazra, S., Goswami, D. P., Macfarlane, P. W. and Sengupta, A. (2017) An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: its emergence and loss. Journal of Electrocardiology, 50(5), pp. 652-660. (doi: 10.1016/j.jelectrocard.2017.03.016) (PMID:28366419)
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Abstract
Aims: To objectively characterize and mathematically justify the observation that vectorcardiographic QRS loops in normal individuals are more planar than those from patients with ST elevation myocardial infarction (STEMI). Methods: Vectorcardiograms (VCGs) were constructed from three simultaneously recorded quasi-orthogonal leads, I, aVF and V2 (sampled at 1000 samples/s). The planarity of these QRS loops was determined by fitting a surface to each loop. Goodness of fit was expressed in numerical terms. Results: 15 healthy individuals aged 35–65 years (73% male) and 15 patients aged 45–70 years (80% male) with diagnosed acute STEMI were recruited. The spatial-QRS loop was found to lie in a plane in normal controls. In STEMI patients, this planarity was lost. Calculation of goodness of fit supported these visual observations. Conclusions: The degree of planarity of the VCG loop can differentiate healthy individuals from patients with STEMI. This observation is compatible with our basic understanding of the electrophysiology of the human heart.
| Item Type: | Articles |
|---|---|
| Keywords: | Healthy controls, QRS plane, STEMI, uniform double layer, vectorcardiogram. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Macfarlane, Professor Peter |
| Authors: | Ray, D., Hazra, S., Goswami, D. P., Macfarlane, P. W., and Sengupta, A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre |
| Journal Name: | Journal of Electrocardiology |
| Publisher: | Elsevier |
| ISSN: | 0022-0736 |
| ISSN (Online): | 1532-8430 |
| Published Online: | 22 March 2017 |
| Copyright Holders: | Copyright © 2017 Elsevier Inc. |
| First Published: | First published in Journal of Electrocardiology 50(5):652-660 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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