Synthesis of veprisine dimers and the formation of a novel cyclic tetramer from precocene I

Ngadjui, B. T., Ayafor, J. F., Bilon, A. E. N., Sondengam, B. L., Connolly, J. D. and Rycroft, D. S. (1992) Synthesis of veprisine dimers and the formation of a novel cyclic tetramer from precocene I. Tetrahedron, 48(40), pp. 8711-8724. (doi: 10.1016/S0040-4020(01)89446-1)

Abstract

Thermolysis of veprisine afforded vepridimerines A–D and in addition, a new dimer, vepridimerine E. The full details of the ¹H and ¹³C NMR spectroscopic properties of vepridimerines A–E are presented. Acid treatment of veprisine gave another new dimer, diveprisine, analogous to the known precocene II dimer. Under the same conditions precocene I was transformed into a cyclic tetramer. High field NMR examination of the coumarin dimer, reported by Barnes et al. in 1963, confirmed the assigned structure.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Connolly, Professor Joseph and Rycroft, Dr David
• Authors: Ngadjui, B. T., Ayafor, J. F., Bilon, A. E. N., Sondengam, B. L., Connolly, J. D., and Rycroft, D. S.
• Subjects: Q Science > QD Chemistry
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Tetrahedron
• Publisher: Elsevier
• ISSN: 0040-4020
• ISSN (Online): 1464-5416
• Published Online: 01 March 2001