Rycroft, D. S., Robins, D. J. and Sadler, I. H. (1992) Revised assignment of the 1H NMR spectrum of the quinolizidine alkaloid lupinine. Magnetic Resonance in Chemistry, 30(13), S15-S17. (doi: 10.1002/mrc.1260301306)
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Abstract
The <sup>1</sup>H NMR spectrum of the quinolizidine alkaloid lupinine was studied at 200 and 600 MHz. A full assignment of the <sup>1</sup>H signals was achieved by application of a variety of NMR techniques, including homonuclear <sup>1</sup>H NOE difference, 2D <i>δ</i>H/<i>δ</i>H COSY and direct <i>δ</i>C/<i>δ</i>H correlation experiments. This results in some changes to the current literature assignments; particularly important is the conclusion that the chemical shift difference between the equatorial (<i>β</i>) and axial (<i>α</i>) protons at C-9 is negative (−0.47 ppm) rather than positive. The currently accepted assignment of the <sup>13</sup>C NMR spectrum has been confirmed by independent, and more direct, means.
Item Type: | Articles |
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Additional Information: | Invited contribution to special issue: Structure elucidation of natural products by NMR. |
Keywords: | NMR spectroscopy. |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Rycroft, Dr David and Robins, Prof David |
Authors: | Rycroft, D. S., Robins, D. J., and Sadler, I. H. |
Subjects: | Q Science > QD Chemistry |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Magnetic Resonance in Chemistry |
Publisher: | John Wiley & Sons, Ltd |
ISSN: | 0749-1581 |
ISSN (Online): | 1097-458X |
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