Spatial memory and hippocampal enhancement

Peters, M., Munoz, M. and Morris, R. G. (2015) Spatial memory and hippocampal enhancement. Current Opinion in Behavioral Sciences, 4, pp. 81-91. (doi: 10.1016/j.cobeha.2015.03.005)

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Abstract

Given the central role of hippocampal function in spatial and episodic memory, the concept of enhancing it when compromised is attractive. This might be realised behaviourally, pharmacologically or via more radical routes such as brain stimulation. Successful approaches in each of these domains include trial-spacing, rest, and NMDA or cholinergic receptor modulation, but the goal of enhancement has to be clear as some approaches can enhance in one domain but inhibit in another. Enhancement may also extend the duration of memory rather than augment encoding, an idea conceptually embedded into the synaptic-tagging-and-capture theory of memory persistence. In addition, recent work on human spatial memory reflects new findings about the interacting components of egocentric and allocentric processing of human navigation.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Munoz, Dr Monica
Authors: Peters, M., Munoz, M., and Morris, R. G.
College/School:College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:Current Opinion in Behavioral Sciences
Publisher:Elsevier
ISSN:2352-1546
Published Online:08 April 2015

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