Blagg, S. L. and Insall, R. H. (2004) Solving the WAVE function. Nature Cell Biology, 6(4), pp. 279-281. (doi: 10.1038/ncb0404-279) (PMID:15057236)
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Abstract
SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Insall, Professor Robert |
| Authors: | Blagg, S. L., and Insall, R. H. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Nature Cell Biology |
| Publisher: | Nature Publishing Group |
| ISSN: | 1465-7392 |
| ISSN (Online): | 1476-4679 |
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