Neural correlates of evidence accumulation during value-based decisions revealed via simultaneous EEG-fMRI

Pisauro, M. A., Fouragnan, E., Retzler, C. and Philiastides, M. G. (2017) Neural correlates of evidence accumulation during value-based decisions revealed via simultaneous EEG-fMRI. Nature Communications, 8, 15808. (doi: 10.1038/ncomms15808) (PMID:28598432) (PMCID:PMC5472767)

138913.pdf - Published Version
Available under License Creative Commons Attribution.



Current computational accounts posit that, in simple binary choices, humans accumulate evidence in favour of the different alternatives before committing to a decision. Neural correlates of this accumulating activity have been found during perceptual decisions in parietal and prefrontal cortex; however the source of such activity in value-based choices remains unknown. Here we use simultaneous EEG-fMRI and computational modelling to identify EEG signals reflecting an accumulation process and demonstrate that the within- and across-trial variability in these signals explains fMRI responses in posterior-medial frontal cortex. Consistent with its role in integrating the evidence prior to reaching a decision, this region also exhibits task-dependent coupling with the ventromedial prefrontal cortex and the striatum, brain areas known to encode the subjective value of the decision alternatives. These results further endorse the proposition of an evidence accumulation process during value-based decisions in humans and implicate the posterior-medial frontal cortex in this process.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Fouragnan, Dr Elsa and Retzler, Mr Christopher and Pisauro, Dr Michele Andrea and Philiastides, Professor Marios
Authors: Pisauro, M. A., Fouragnan, E., Retzler, C., and Philiastides, M. G.
College/School:College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
Journal Name:Nature Communications
Publisher:Nature Research
ISSN (Online):2041-1723
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Nature Communications 8:15808
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
653861Spatiotemporal characterization of value judgments and reward processing in the human brainMarios PhiliastidesBiotechnology and Biological Sciences Research Council (BBSRC)BB/J015393/2INP - CENTRE FOR COGNITIVE NEUROIMAGING
654411Neural correlates of learning and confidence during decision making and their utility in developing "intelligent technologies".Marios PhiliastidesEconomic & Social Research Council (ESRC)ES/L012995/1INP - CENTRE FOR COGNITIVE NEUROIMAGING