Marti, M. , Li, Y., Köhler, P. and Hehl, A. B. (2002) Conformationally correct expression of membrane-anchored Toxoplasma gondii SAG1 in the primitive protozoan Giardia duodenalis. Infection and Immunity, 70(2), pp. 1014-1016. (doi: 10.1128/IAI.70.2.1014-1016.2002) (PMID:11796643) (PMCID:PMC127713)
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Abstract
To explore the possibility of expressing membrane-anchored exodomains of heterologous surface antigens in Giardia, a chimeric construct containing the Toxoplasma gondii SAG1 gene was made. The Giardia system is shown here to provide a means of generating correctly folded chimeric surface proteins in a native and unmodified form.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Marti, Professor Matthias |
Authors: | Marti, M., Li, Y., Köhler, P., and Hehl, A. B. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Infection and Immunity |
Publisher: | American Society for Microbiology |
ISSN: | 0019-9567 |
ISSN (Online): | 1098-5522 |
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