Havlik, J. , Budesinsky, M., Kloucek, P., Kokoska, L., Valterova, I., Vasickova, S. and Zeleny, V. (2009) Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil. Phytochemistry, 70(3), pp. 414-418. (doi: 10.1016/j.phytochem.2008.12.018) (PMID:19195668)
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Abstract
A detailed analysis of Rhaponticum carthamoides (Willd.) Iljin root essential oil was carried out by GC, GC–MS and GC–FTIR techniques. In total, 30 components were identified, accounting for 98.0% of total volatiles. A norsesquiterpene 13-norcypera-1(5),11(12)-diene (22.6%), followed by aplotaxene (21.2%) and cyperene (17.9%), were isolated and their structures confirmed by 1D and 2D-NMR spectra (COSY, ROESY, HSQC, HMBC and INADEQUATE). Selinene type sesquiterpenes and aliphatic hydrocarbons were among minor constituents of the essential oil. The oil exhibited antimicrobial activity against 5 of 9 strains of bacteria and yeast, when tested using broth micro-dilution method. Minimum inhibitory concentrations ranged between 32 and 256 μg/ml.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Havlik, Dr Jaroslav |
| Authors: | Havlik, J., Budesinsky, M., Kloucek, P., Kokoska, L., Valterova, I., Vasickova, S., and Zeleny, V. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | Phytochemistry |
| Publisher: | Elsevier |
| ISSN: | 0031-9422 |
| ISSN (Online): | 1873-3700 |
| Published Online: | 03 February 2009 |
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