3D-printed devices for continuous-flow organic chemistry

Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J. and Cronin, L. (2013) 3D-printed devices for continuous-flow organic chemistry. Beilstein Journal of Organic Chemistry, 9, pp. 951-959. (doi: 10.3762/bjoc.9.109) (PMID:23766811) (PMCID:PMC3678713)

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We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR flow cell. As a proof of concept, we utilized two types of organic reactions, imine syntheses and imine reductions, to show how different reactor configurations and substrates give different products.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Kitson, Dr Philip and Rosnes, Dr Mali and Cronin, Professor Lee and Sans Sangorrin, Dr Victor
Authors: Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J., and Cronin, L.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Beilstein Journal of Organic Chemistry
ISSN (Online):1860-5397
Copyright Holders:Copyright © 2013 Dragone et al.
First Published:First published in Beilstein Journal of Organic Chemistry 9:951-959
Publisher Policy:Reproduced under a creative commons license

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