Pei, C., Barbour, M., Fairlie-Clarke, K. J., Allan, D., Mu, R. and Jiang, H.-R. (2014) Emerging role of interleukin-33 in autoimmune diseases. Immunology, 141(1), pp. 9-17. (doi: 10.1111/imm.12174) (PMID:24116703)
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Abstract
Interleukin-33 (IL-33) is a member of the IL-1 cytokine family. It predominantly induces type 2 immune responses and thus is protective against atherosclerosis and nematode infections but contributes to allergic airway inflammation. Interleukin-33 also plays a pivotal role in the development of many autoimmune diseases through mechanisms that are still not fully understood. In this review, we focus on the recent advances in understanding of the expression and function of IL-33 in some autoimmune disorders, aiming to provide insight into its potential role in disease development.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Fairlie-Clarke, Dr Karen and Jiang, Dr Hui-Rong |
| Authors: | Pei, C., Barbour, M., Fairlie-Clarke, K. J., Allan, D., Mu, R., and Jiang, H.-R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Immunology |
| Publisher: | Wiley |
| ISSN: | 0019-2805 |
| ISSN (Online): | 1365-2567 |
| Published Online: | 10 December 2013 |
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