Gao, H. , Qi, N., Feng, L., Ma, X., Danton, M., Berry, C. and Luo, X. (2017) Modelling mitral valvular dynamics–current trend and future directions. International Journal for Numerical Methods in Biomedical Engineering, 33(10), e2858. (doi: 10.1002/cnm.2858) (PMID:27935265) (PMCID:PMC5697636)
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Abstract
Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment, prevention and diagnosis of mitral valve diseases. Compared with the aortic valve, the mitral valve has been much less studied owing to its highly complex structure and strong interaction with the blood flow and the ventricles. However, the interest in mitral valve modelling is growing, and the sophistication level is increasing with the advanced development of computational technology and imaging tools. This review summarises the state-of-the-art modelling of the mitral valve, including static and dynamics models, models with fluid-structure interaction, and models with the left ventricle interaction. Challenges and future directions are also discussed.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Luo, Professor Xiaoyu and Danton, Mr Mark and Qi, Dr Nan and Gao, Dr Hao and Feng, Mr Liuyang and Berry, Professor Colin |
| Authors: | Gao, H., Qi, N., Feng, L., Ma, X., Danton, M., Berry, C., and Luo, X. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing College of Science and Engineering > School of Mathematics and Statistics > Mathematics |
| Journal Name: | International Journal for Numerical Methods in Biomedical Engineering |
| Publisher: | Wiley |
| ISSN: | 2040-7939 |
| ISSN (Online): | 2040-7947 |
| Published Online: | 16 February 2017 |
| Copyright Holders: | Copyright © 2017 The Authors |
| First Published: | First published in International Journal for Numerical Methods in Biomedical Engineering 33(10):e2858 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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