A protocol for a systematic review of clinical guidelines and published systematic reviews on the early detection of oral cancer

Al Bulushi, N. M., Macpherson, L. M.D. , Worlledge-Andrew, H. , Gibson, J., Ross, A. J. and Conway, D. I. (2016) A protocol for a systematic review of clinical guidelines and published systematic reviews on the early detection of oral cancer. Translational Research in Oral Oncology, 1, 2057178X16. (doi: 10.1177/2057178X16658308)

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Background: The predicted increase in incidence of oral cavity cancer (OCC) coupled with high mortality and poor prognosis – particularly when diagnosed at a late/advanced stage – highlights the need for prevention and early detection/screening to reverse these trends. Dental healthcare professionals in primary care settings have a pivotal role in this effort. Aim: The aim of this protocol is to detail the process for assessing the evidence for the best practice and methods of early detection/screening for OCC in primary care dental settings by undertaking a systematic review of global clinical guidelines and published systematic reviews. Method: Searches for clinical guidelines and systematic reviews will be conducted in the following databases: Cochrane library, Medical Literature Analysis and Retrieval System Online (Ovid), Excerpta Medical dataBASE, PubMed, Turning Research into Practice, SCOPUS and Web of Science Core Collection. Our search will extend to include Google Scholar and international professional organizations/associations websites. In addition, we will handsearch the bibliographies and undertake citation searches of the selected papers. Quality appraisal will be undertaken using the Appraisal of Guidelines for Research and Evaluation version II instrument for the clinical guidelines and both A MeaSurement Tool to Assess Systematic Reviews and Risk of Bias in Systematic Reviews tools for the systematic reviews. A narrative synthesis approach will be used to assess the evidence of extracted data, primarily taking account of quality appraisal and recency of publication. Discussion: The synthesis of evidence will determine best practice for OCC early detection/screening by primary care dental healthcare professionals and will evaluate the relationship between clinical guidelines and the evidence base available from systematic reviews in this area.

Item Type:Articles
Additional Information:This project received funding from Ministry of Health, Sultanate of Oman.
Glasgow Author(s) Enlighten ID:Worlledge-Andrew, Mrs Heather and Macpherson, Professor Lorna and Gibson, Professor John and Ross, Dr Alastair and Conway, Professor David
Authors: Al Bulushi, N. M., Macpherson, L. M.D., Worlledge-Andrew, H., Gibson, J., Ross, A. J., and Conway, D. I.
Subjects:R Medicine > RK Dentistry
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
University Services > Library and Collection Services > Library
Journal Name:Translational Research in Oral Oncology
Publisher:SAGE Publications
ISSN (Online):2057-178X
Copyright Holders:Copyright © 2016 The Authors
First Published:First published in Translational Research in Oral Oncology 1: 2057178X16
Publisher Policy:Reproduced under a Creative Commons License

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