The oncogenic potential of Epstein-Barr virus nuclear antigen 1 in transgenic mice

Wilson, J.B. and Levine, A.J. (1992) The oncogenic potential of Epstein-Barr virus nuclear antigen 1 in transgenic mice. Current Topics in Microbiology and Immunology, 182, pp. 375-384. (doi:10.1007/978-3-642-77633-5_48) (PMID:337032)

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Abstract

The human herpes virus, Epstein-Barr virus (EBV) is highly prevalent among all communities. Although largely asymptomatic prior to puberty it is the etiologic agent of the lymphoproliferative disorder, infectious mononucleosis. The virus is also tightly associated with two major forms of human B-cell malignancy: endemic Burkitt’s lymphoma (BL) and the lymphomas to which immunosupressed individuals are prone (for review see Epstein and Achong, 1986).

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Wilson, Professor Joanna
Authors: Wilson, J.B., and Levine, A.J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Current Topics in Microbiology and Immunology
Publisher:Springer
ISSN:0070-217X

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