Neil, J. C. , Cameron, E. R. and Baxter, E. W. (1997) p53 and tumour viruses: catching the guardian off-guard. Trends in Microbiology, 5(3), pp. 115-120. (doi: 10.1016/S0966-842X(96)10083-4) (PMID:9080610)
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Abstract
Oncogenic viruses have evolved direct and indirect mechanisms to overcome the tumour suppressor p53. Fortunately, tumour development is limited by the narrow cell tropisms of the viruses concerned and the host immune response. However, such viruses are helping to elucidate the p53 response pathway and may play a future role as novel cancer therapeutic agents.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Cameron, Professor Ewan and Neil, Professor James |
Authors: | Neil, J. C., Cameron, E. R., and Baxter, E. W. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Trends in Microbiology |
Publisher: | Elsevier |
ISSN: | 0966-842X |
ISSN (Online): | 1878-4380 |
Published Online: | 09 December 1997 |
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