Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast

Budde, J., Shajan, G. , Hoffmann, J., Uğurbil, K. and Pohmann, R. (2011) Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast. Magnetic Resonance in Medicine, 65(2), pp. 544-550. (doi: 10.1002/mrm.22632) (PMID:20872858)

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The effect of susceptibility differences on an MR image is known to increase with field strength. Magnetic field inhomogeneities within the voxels influence the apparent transverse relaxation time T2*, while effects due to different precession frequencies between voxels caused by local field variations are evident in the image phase, and susceptibility-weighted imaging highlights the veins and deep brain structures. Here, these three contrast mechanisms are examined at a field strength of 9.4 T. The T2* maps generated allow the identification of white matter structures not visible in conventional images. Phase images with in-plane resolutions down to 130 μm were obtained, showing high gray/white matter contrast and allowing the identification of internal cortical structures. The susceptibility-weighted images yield excellent visibility of small venous structures and attain an in-plane resolution of 175 μm.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Gunamony, Dr Shajan
Authors: Budde, J., Shajan, G., Hoffmann, J., Uğurbil, K., and Pohmann, R.
College/School:College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
Journal Name:Magnetic Resonance in Medicine
ISSN (Online):1522-2594
Published Online:24 September 2010

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