Endothelial dysfunction in human essential hypertension

Mordi, I., Mordi, N., Delles, C. and Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34(8), pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965) (PMID:27203578)

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Abstract

Although the endothelium has a number of important functions, the term endothelial dysfunction is commonly used to describe impairment in its vasodilatory capacity. It is increasingly recognized that this is related to hypertension, although whether it predates essential hypertension or is a consequence of it is still unknown. In this review, we explore the mechanisms of endothelial dysfunction in essential hypertension, its prognostic significance and methods of pharmacological reversal.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Tzemos, Dr Nikolaos and Delles, Professor Christian and Mordi, Dr Ify
Authors: Mordi, I., Mordi, N., Delles, C., and Tzemos, N.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:Journal of Hypertension
Publisher:Lippincott, Williams & Wilkins
ISSN:0263-6352
ISSN (Online):1473-5598
Copyright Holders:Copyright © 2016 Wolters Kluwer Health, Inc.
First Published:First published in Journal of Hypertension 34(8): 1464-1472
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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