Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey

Svolos, V. et al. (2017) Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey. BMC Gastroenterology, 17, 14. (doi: 10.1186/s12876-016-0564-7) (PMID:28103809) (PMCID:PMC5247812)

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Background: Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of EEN and alternative novel, solid food-based diets (SFDs) expressed by paediatric patients with CD, previously treated with EEN and their parents. Methods: This anonymous questionnaire surveyed families of CD patients treated with EEN over 1 year. Two questionnaire forms were completed; one asking the patients’ opinions and another referring to their main carer. This questionnaire explored participants’ demographic characteristics; acceptability of a repeat EEN course to treat a future flare (EEN repeat); their opinion on how difficult EEN would be compared to an example SFD; and their intention to participate in a future clinical trial assessing the therapeutic efficacy of an SFD in CD. Results: Forty-one families of CD patients were approached with 29 sending replies (71%). Most of our participants were positive on completing another EEN course, however the majority would choose an SFD alternative (Patients: 66, Parents:72%). Both patients and their parents rated EEN to be more difficult to adhere to compared to an example SFD (p < 0.05), and their ratings were strongly correlated (EEN:r = 0.83, SFD:r = 0.75, p < 0.001). The majority of our respondents would agree to participate in a clinical trial assessing an SFD’s effectiveness (Patients:79, Parents:72%) for the management of active CD. Conclusions: While patients with CD and their families would accept an EEN repeat, the majority would prefer an SFD alternative. CD families surveyed are supportive of the development of solid food-based dietary treatments.

Item Type:Articles
Additional Information:The authors are supported by the Glasgow Children’s Hospital Charity and the Catherine McEwan Foundation.
Glasgow Author(s) Enlighten ID:Hansen, Dr Richard and Russell, Dr Richard and Gaya, Mr Daniel and Gerasimidis, Professor Konstantinos and Svolos, Dr Vaios
Authors: Svolos, V., Gerasimidis, K., Buchanan, E., Curtis, L., Garrick, V., Hay, J., Laird, S., Munro, J., Gaya, D. R., Russell, R. K., and Hansen, R.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:BMC Gastroenterology
Publisher:BioMed Central
ISSN (Online):1471-230X
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in BMC Gastroenterology 17: 14
Publisher Policy:Reproduced under a Creative Commons License

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