Currie, G. and Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18(7), 54. (doi: 10.1007/s11906-016-0661-6) (PMID:27221728)
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Abstract
The current definition of hypertension is based on blood pressure values, and blood pressure also drives treatment decisions, is the most important treatment monitoring tool and helps estimating risk of hypertension related organ damage. In an era of precision medicine additional biomarkers are needed in the diagnosis and management of patients with hypertension. In this review we outline the areas in which functional, imaging and circulating biomarkers could help in a more individualised definition of hypertension and associated risk. We will cover biomarkers for diagnosis; of pathophysiology and prediction of hypertension; response to treatment, organ damage; and to monitor treatment. A clear focus is on the vasculature, the heart and the kidneys, whereas we see a need to further develop biomarkers of cerebral function in order to diagnose cognition deficits and monitor changes in cognition in the future to support addressing the growing burden of hypertension associated vascular dementia.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Delles, Professor Christian and Currie, Dr Gemma |
| Authors: | Currie, G., and Delles, C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Current Hypertension Reports |
| Publisher: | Springer US |
| ISSN: | 1522-6417 |
| ISSN (Online): | 1534-3111 |
| Published Online: | 24 May 2016 |
| Copyright Holders: | Copyright © 2016 Springer Science+Business Media New York |
| First Published: | First published in Current Hypertension Reports 18(7):54 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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