Critical care provision after colorectal cancer surgery

Dale, C.D., McLoone, P. , Sloan, B., Kinsella, J., Morrison, D., Puxty, K. and Quasim, T. (2016) Critical care provision after colorectal cancer surgery. BMC Anesthesiology, 16, 94. (doi: 10.1186/s12871-016-0243-9) (PMID:27733119) (PMCID:PMC5059906)

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Background: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to identify pre-operative risk factors that increased the likelihood of this occurring. Methods: This is a retrospective observational study of all 6441 patients who underwent colorectal cancer surgery within the West of Scotland Region between 2005 and 2011. Logistic regression was employed to determine factors associated with receiving postoperative organ support. Results: A total of 610 (9 %) patients received organ support. Multivariate analysis identified age ≥65, male gender, emergency surgery, social deprivation, heart failure and type II diabetes as being independently associated with organ support postoperatively. After adjusting for demographic and clinical factors, patients with metastatic disease appeared less likely to receive organ support (p = 0.012). Conclusions: Nearly one in ten patients undergoing CRC surgery receive organ support in the post operative period. We identified several risk factors which increase the likelihood of receiving organ support post operatively. This is relevant when consenting patients about the risks of CRC surgery.

Item Type:Articles
Glasgow Author(s) Enlighten ID:McLoone, Mr Philip and Morrison, Dr David and Quasim, Professor Tara and Kinsella, Professor John and Puxty, Dr Kathryn
Authors: Dale, C.D., McLoone, P., Sloan, B., Kinsella, J., Morrison, D., Puxty, K., and Quasim, T.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:BMC Anesthesiology
Publisher:BioMed Central
ISSN (Online):1471-2253
Copyright Holders:Copyright © 2016 The Authors
First Published:First published in BMC Anesthesiology 16: 94
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
604521Outcome of cancer patients with critical illness requiring intensive care admissionDavid MorrisonCancer Research UK (CAN-RES-UK)16662IHW - PUBLIC HEALTH