A 966-Electrode Neural Probe with 384 Configurable Channels in 0.13µm SOI CMOS

Lopez, C. M. et al. (2016) A 966-Electrode Neural Probe with 384 Configurable Channels in 0.13µm SOI CMOS. In: IEEE international Solid-State Circuits Conference (ISSCC), San Fransisco, CA, 31 Jan - 4 Feb 2016, pp. 392-393. ISBN 9781467394666 (doi: 10.1109/ISSCC.2016.7418072)

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Abstract

In vivo recording of neural action-potential (AP) and local-field-potential (LFP) signals requires the use of high-resolution penetrating probes. Driven by the need for large-scale recording and minimal tissue damage, a technology roadmap has been defined for next-generation probes aiming to maximize the number of recording sites while minimizing the probe dimensions [1]. In this paper we present a 384-channel configurable active neural probe for high-density recording which implements in situ buffering under each electrode to minimize the crosstalk between adjacent metal lines along the shank and other parasitic effects inherent to traditional passive probes [2]. Up to 966 selectable, neuron-sized electrodes (12×12μm2) were densely packed along a narrow (70μm) and thin (20μm) implantable shank using integrated CMOS. With twice the number of electrodes compared to state-of-the-art neural probes [2], our design achieves the highest electrode count in a single shank reported so far.

Item Type:Conference Proceedings
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Mitra, Dr Srinjoy
Authors: Lopez, C. M., Mitra, S., Putzeys, J., Raducanu, B., Ballini, M., Andrei, A., Severi, S., Welkenhuysen, M., Van Hoof, C., Musa, S., and Yazicioglu, R. F.
College/School:College of Science and Engineering > School of Engineering
ISBN:9781467394666
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