Braceland, M., Houston, K., Ashby, A., Matthews, C., Haining, H., Rodger, H. and Eckersall, P.D. (2017) Technical pre-analytical effects on the clinical biochemistry of Atlantic salmon (Salmo salar L.). Journal of Fish Diseases, 40(1), pp. 29-40. (doi: 10.1111/jfd.12476) (PMID:27145526) (PMCID:PMC5215511)
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Abstract
Clinical biochemistry has long been utilized in human and veterinary medicine as a vital diagnostic tool, but despite occasional studies showing its usefulness in monitoring health status in Atlantic salmon (Salmo salar L.), it has not yet been widely utilized within the aquaculture industry. This is due, in part, to a lack of an agreed protocol for collection and processing of blood prior to analysis. Moreover, while the analytical phase of clinical biochemistry is well controlled, there is a growing understanding that technical pre-analytical variables can influence analyte concentrations or activities. In addition, post-analytical interpretation of treatment effects is variable in the literature, thus making the true effect of sample treatment hard to evaluate. Therefore, a number of pre-analytical treatments have been investigated to examine their effect on analyte concentrations and activities. In addition, reference ranges for salmon plasma biochemical analytes have been established to inform veterinary practitioners and the aquaculture industry of the importance of clinical biochemistry in health and disease monitoring. Furthermore, a standardized protocol for blood collection has been proposed.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Braceland, Mr Mark and Eckersall, Professor David and Haining, Dr Hayley |
| Authors: | Braceland, M., Houston, K., Ashby, A., Matthews, C., Haining, H., Rodger, H., and Eckersall, P.D. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Journal of Fish Diseases |
| Publisher: | Wiley |
| ISSN: | 0140-7775 |
| ISSN (Online): | 1365-2761 |
| Published Online: | 04 May 2016 |
| Copyright Holders: | Copyright © 2016 The Authors |
| First Published: | First published in Journal of Fish Diseases 40(1): 29-40 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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