Assessment of degree of risk from sources of microbial contamination in cleanrooms; 2: surfaces and liquids

Whyte, W. and Eaton, T. (2015) Assessment of degree of risk from sources of microbial contamination in cleanrooms; 2: surfaces and liquids. European Journal of Parenteral and Pharmaceutical Sciences, 20(4), pp. 117-126.

Abstract

The degree of risk from microbial contamination of manufactured products in healthcare cleanrooms has been assessed in a series of three articles. The first article discussed airborne sources, and this second article considers surface contact and liquid sources. A final article will consider all sources and give further information on the application of the risk method. The degree of risk to products from micro-organisms transferred from sources by surface contact, or by liquids, has been assessed by the means of fundamental equations used to calculate the likely number of microbes deposited (NMD) onto, or into, a product. The method calculates the likely product contamination rate from each source and gives a more accurate risk assessment than those presently available. It also allows a direct comparison to be made between microbial transfer by different routes, i.e. surface, liquid and air.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Whyte, Dr William
• Authors: Whyte, W., and Eaton, T.
• College/School: College of Science and Engineering > School of Engineering
• Journal Name: European Journal of Parenteral and Pharmaceutical Sciences
• Publisher: Euromed Communications
• ISSN: 0964-4679
• ISSN (Online): 1740-6277
• Copyright Holders: Copyright © 2015 Euromed Communications
• First Published: First published in European Journal of Parenteral and Pharmaceutical Sciences 20(4):117-126
• Publisher Policy: Reproduced with the permission of the publisher.