Olsen, J. R. , Gallacher, J., Finlay, A. Y., Piguet, V. and Francis, N. A. (2016) Quality of life impact of childhood skin conditions measured using the children’s dermatology life quality index (CDLQI): a meta-analysis. British Journal of Dermatology, 174(43), pp. 853-861. (doi: 10.1111/bjd.14361) (PMID:26686685)
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Abstract
Background: The Children’s Dermatology Life Quality Index (CDLQI) is the most widely used instrument for measuring the impact of skin disease on quality of life (QoL) in children. Objective: Provide a meta-analysis of all published quality of life (QoL) scores for a range of childhood skin conditions. Methods: Studies using the Children’s Dermatology Life Quality Index (CDLQI) questionnaire to measure QoL in skin conditions were identified by searching Medline and Embase from January 1995 (CDLQI creation) to December 2014. Studies were grouped according to condition and baseline scores were combined using meta-analysis. Results: 67 studies using the CDLQI met the inclusion criteria. The overall estimated CDLQI scores for conditions reported more than once were: atopic eczema (Point Estimate 8.5 (95% CI 7.1-9.8), number of studies = 38, score range = 0-29), acne (5.3 (1.9-8.5), n=5, 0-30), alopecia (3.1 (0-7.7), n=2, 0-6), molluscum contagiosum (3.5 (0.6-6.7), n=5, 0-27), psoriasis (8.0 (3.9-12.1), n=6, 0-29), scabies (9.2 (0.0-20.3), n=2, 1-26), urticaria (7.1 (0-15.4), n=2, 0-22), vitiligo (6.5 (0.7-12.2), n=2, 0-20), and warts (2.9 (0-5.8), n=4, 0-16). Overall, the mean effect on QoL (weighted average CDLQI score 4.6 (95% CI 3.9 to 5.4)) for children with these conditions was small. However, many children were found to experience a very large impact on QoL (34% of children with atopic eczema, 10% with molluscum contagiosum and 1 - 5% with acne) in studies where the distributions of scores were provided. Conclusions: Most skin conditions in children have a “small” mean effect on quality of life. However, the range is large and a significant proportion of children with many common skin conditions will experience a very large effect on quality of life.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Olsen, Dr Jonathan |
| Authors: | Olsen, J. R., Gallacher, J., Finlay, A. Y., Piguet, V., and Francis, N. A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health |
| Journal Name: | British Journal of Dermatology |
| Publisher: | Wiley-Blackwell Publishing Ltd. |
| ISSN: | 0007-0963 |
| ISSN (Online): | 1365-2133 |
| Published Online: | 06 March 2016 |
| Copyright Holders: | Copyright © 2015 ritish Association of Dermatologists |
| First Published: | First published in British Journal of Dermatology 174(4):853-861 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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