Simultaneous measurement of thermophysical properties of tissue-mimicking phantoms for high intensity focused ultrasound (HIFU) exposures

Gao, J., You, J., Huang, Z., Cochran, S. and Corner, G. (2012) Simultaneous measurement of thermophysical properties of tissue-mimicking phantoms for high intensity focused ultrasound (HIFU) exposures. International Journal of Thermophysics, 33(3), pp. 495-504. (doi: 10.1007/s10765-012-1158-4)

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Abstract

Tissue-mimicking phantoms, including bovine serum albumin phantoms and egg white phantoms, have been developed for, and in laboratory use for, real-time visualization of high intensity focused ultrasound-induced thermal coagulative necrosis since 2001. However, until now, very few data are available concerning their thermophysical properties. In this article, a step-wise transient plane source method has been used to determine the values of thermal conductivity, thermal diffusivity, and specific heat capacity of egg white phantoms with elevated egg white concentrations (0 v/v% to 40 v/v%, by 10 v/v% interval) at room temperature (~20 °C). The measured thermophysical properties were close to previously reported values; the thermal conductivity and thermal diffusivity were linearly proportional to the egg white concentration within the investigation range, while the specific heat capacity decreased as the egg white concentration increased. Taking account of large differences between real experiment and ideal model, data variations within 20 % were accepted.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cochran, Professor Sandy
Authors: Gao, J., You, J., Huang, Z., Cochran, S., and Corner, G.
College/School:College of Science and Engineering > School of Engineering > Systems Power and Energy
Journal Name:International Journal of Thermophysics
Publisher:Springer US
ISSN:0195-928X
ISSN (Online):1572-9567

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