Mechanical compatibility of sol–gel annealing with titanium for orthopaedic prostheses

Greer, A. I. M. , Lim, T. S., Brydone, A. S. and Gadegaard, N. (2016) Mechanical compatibility of sol–gel annealing with titanium for orthopaedic prostheses. Journal of Materials Science: Materials in Medicine, 27, 21. (doi: 10.1007/s10856-015-5611-3) (PMID:26691162) (PMCID:PMC4686541)

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Abstract

Sol–gel processing is an attractive method for large-scale surface coating due to its facile and inexpensive preparation, even with the inclusion of precision nanotopographies. These are desirable traits for metal orthopaedic prostheses where ceramic coatings are known to be osteoinductive and the effects may be amplified through nanotexturing. However there are a few concerns associated with the application of sol–gel technology to orthopaedics. Primarily, the annealing stage required to transform the sol–gel into a ceramic may compromise the physical integrity of the underlying metal. Secondly, loose particles on medical implants can be carcinogenic and cause inflammation so the coating needs to be strongly bonded to the implant. These concerns are addressed in this paper. Titanium, the dominant material for orthopaedics at present, is examined before and after sol–gel processing for changes in hardness and flexural modulus. Wear resistance, bending and pull tests are also performed to evaluate the ceramic coating. The findings suggest that sol–gel coatings will be compatible with titanium implants for an optimum temperature of 500 °C.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Greer, Dr Andrew and Gadegaard, Professor Nikolaj
Authors: Greer, A. I. M., Lim, T. S., Brydone, A. S., and Gadegaard, N.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Journal of Materials Science: Materials in Medicine
Publisher:Springer US
ISSN:1573-4838
ISSN (Online):1573-4838
Copyright Holders:Copyright © 2015 The Authors
First Published:First published in Journal of Materials Science: Materials in Medicine 27:21
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
548641Bioactive orthopaedic implants using nanopatterned 3D materialsNikolaj GadegaardMedical Research Council (MRC)G1000842ENG - BIOMEDICAL ENGINEERING