Gourlay, C.W. and Ayscough, K. (2005) The actin cytoskeleton: a key regulator of apoptosis and ageing? Nature Reviews Molecular Cell Biology, 6(7), 583-5U5. (doi: 10.1038/nrm1682)
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Abstract
Evidence from many organisms has shown that the accumulation of reactive oxygen species (ROS) has a detrimental effect on cell well-being. High levels of ROS have been linked to programmed cell death pathways and to ageing. Recent reports have implicated changes to the dynamics of the actin cytoskeleton in the release of ROS from mitochondria and subsequent cell death.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | UNSPECIFIED |
| Authors: | Gourlay, C.W., and Ayscough, K. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | Nature Reviews Molecular Cell Biology |
| ISSN: | 1471-0072 |
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