Mother–infant interaction in schizophrenia: transmitting risk or resilience? A systematic review of the literature

Davidsen, K. A., Harder, S., MacBeth, A., Lundy, J.-M. and Gumley, A. (2015) Mother–infant interaction in schizophrenia: transmitting risk or resilience? A systematic review of the literature. Social Psychiatry and Psychiatric Epidemiology, 50(12), pp. 1785-1798. (doi: 10.1007/s00127-015-1127-x) (PMID:26454698)

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Purpose: The parent–infant relationship is an important context for identifying very early risk and resilience factors and targets for the development of preventative interventions. The aim of this study was to systematically review studies investigating the early caregiver–infant relationship and attachment in offspring of parents with schizophrenia. Methods: We searched computerized databases for relevant articles investigating the relationship between early caregiver–infant relationship and outcomes for offspring of a caregiver with a diagnosis of schizophrenia. Studies were assessed for risk of bias. Results: We identified 27 studies derived from 10 cohorts, comprising 208 women diagnosed with schizophrenia, 71 with other psychoses, 203 women with depression, 59 women with mania/bipolar disorder, 40 with personality disorder, 8 with unspecified mental disorders and 119 non-psychiatric controls. There was some evidence to support disturbances in maternal behaviour amongst those with a diagnosis of schizophrenia and there was more limited evidence of disturbances in infant behaviour and mutuality of interaction. Conclusions: Further research should investigate both sources of resilience and risk in the development of offspring of parents with a diagnosis of schizophrenia and psychosis. Given the lack of specificity observed in this review, these studies should also include maternal affective disorders including depressive and bipolar disorders.

Item Type:Articles
Glasgow Author(s) Enlighten ID:MacBeth, Mr Angus and Gumley, Professor Andrew and Lundy, Dr Jenna-Marie
Authors: Davidsen, K. A., Harder, S., MacBeth, A., Lundy, J.-M., and Gumley, A.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing
Journal Name:Social Psychiatry and Psychiatric Epidemiology
Publisher:Springer Berlin Heidelberg
ISSN (Online):1433-9285
Copyright Holders:Copyright © 2015 The Authors
First Published:First published in Social Psychiatry and Psychiatric Epidemiology 50(12):1785-1798
Publisher Policy:Reproduced under a Creative Commons License

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