Physiotherapy rehabilitation for people with progressive Multiple Sclerosis: a systematic review

Campbell, E. , Coulter, E. H. , Mattison, P. G., Miller, L., McFadyen, A. and Paul, L. (2015) Physiotherapy rehabilitation for people with progressive Multiple Sclerosis: a systematic review. Archives of Physical Medicine and Rehabilitation, 97(1), 141-151.e3. (doi: 10.1016/j.apmr.2015.07.022) (PMID:26281954)

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Abstract

Objective: To assess the efficacy of physiotherapy interventions, including exercise therapy, for the rehabilitation of people with progressive Multiple Sclerosis. Data Sources: Five databases (Cochrane Library, Physiotherapy Evidence Database (PEDro), Web of Science Core Collections, Medline, EMBASE) and reference lists of relevant articles were searched. Study Selection: Randomised experimental trials which included participants with progressive multiple sclerosis and investigated a physiotherapy intervention or an intervention containing a physiotherapy element were included. Data Extraction: Data were independently extracted using a standardised form and methodological quality was assessed using the PEDro scale. Data Synthesis: Thirteen studies (described by 15 articles) were identified; scoring between 5 and 9 out of 10 on the PEDro scale. Eight interventions were assessed: exercise therapy, multi-disciplinary rehabilitation, functional electrical stimulation, botulinum toxin type A injections and manual stretches, inspiratory muscle training, therapeutic standing, acupuncture and body weight supported treadmill training. All studies, apart from one, produced positive results in at least one outcome measure, however, only one article used a power calculation to determine their sample size and due to ‘drop outs’ the results were subsequently underpowered. Conclusions: This review suggests that physiotherapy may be effective for the rehabilitation of people with progressive Multiple Sclerosis. However, further appropriately powered studies are required.

Item Type:Articles (Other)
Keywords:Multiple Sclerosis, physical therapy modalities, exercise, rehabilitation, review
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Campbell, Mr Evan and Coulter, Dr Elaine and Paul, Dr Lorna
Authors: Campbell, E., Coulter, E. H., Mattison, P. G., Miller, L., McFadyen, A., and Paul, L.
Subjects:R Medicine > RZ Other systems of medicine
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Nursing and Health Care
Research Group:Rehabilitation Research Group
Journal Name:Archives of Physical Medicine and Rehabilitation
Publisher:Elsevier
ISSN:0003-9993
ISSN (Online):1532-821X
Copyright Holders:Copyright © 2015 Elsevier Ltd.
First Published:First published in Archives of Physical Medicine and Rehabilitation 97(1):141-151.e3
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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