Common methods for the chiral determination of amphetamine and related compounds I: gas, liquid and thin-layer chromatography

Płotka, J. M., Biziuk, M. and Morrison, C. (2011) Common methods for the chiral determination of amphetamine and related compounds I: gas, liquid and thin-layer chromatography. Trends in Analytical Chemistry, 30(7), pp. 1139-1158. (doi: 10.1016/j.trac.2011.03.013)

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Abstract

This article reviews the most common, useful methods for the chiral determination of amphetamine (AM) and AM-derived designer drugs in different of matrix, including blood, hair, urine, medicaments or standard solutions, taking into consideration articles published in the past 15 years. We consider chromatographic methods (e.g., gas, liquid, high-performance liquid, and thin layer). We describe several types of chiral derivatization reagent, mobile-phase additive and chiral stationary phase commonly used in the chromatographic methods. Tables summarize basic information about conditions (e.g., type of column and mobile phase), detection mode and reference data for each procedure.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Morrison, Dr Calum
Authors: Płotka, J. M., Biziuk, M., and Morrison, C.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Trends in Analytical Chemistry
Publisher:Elsevier B.V.
ISSN:0165-9936
ISSN (Online):1879-3142

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