Pernet, C. R. et al. (2015) The human voice areas: spatial organisation and inter-individual variability in temporal and extra-temporal cortices. NeuroImage, 119, pp. 164-174. (doi: 10.1016/j.neuroimage.2015.06.050) (PMID:26116964) (PMCID:PMC4768083)
|
Text
107613.pdf - Published Version Available under License Creative Commons Attribution. 2MB |
Abstract
fMRI studies increasingly examine functions and properties of non-primary areas of human auditory cortex. However there is currently no standardized localization procedure to reliably identify specific areas across individuals such as the standard ‘localizers’ available in the visual domain. Here we present an fMRI ‘voice localizer’ scan allowing rapid and reliable localization of the voice-sensitive ‘temporal voice areas’ (TVA) of human auditory cortex. We describe results obtained using this standardized localizer scan in a large cohort of normal adult subjects. Most participants (94%) showed bilateral patches of significantly greater response to vocal than non-vocal sounds along the superior temporal sulcus/gyrus (STS/STG). Individual activation patterns, although reproducible, showed high inter-individual variability in precise anatomical location. Cluster analysis of individual peaks from the large cohort highlighted three bilateral clusters of voice-sensitivity, or “voice patches” along posterior (TVAp), mid (TVAm) and anterior (TVAa) STS/STG, respectively. A series of extra-temporal areas including bilateral inferior prefrontal cortex and amygdalae showed small, but reliable voice-sensitivity as part of a large-scale cerebral voice network. Stimuli for the voice localizer scan and probabilistic maps in MNI space are available for download.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Crabbe, Mrs Frances and Bestelmeyer, Dr Patricia and Latinus, Dr Marianne and McAleer, Dr Phil and Belin, Professor Pascal and Charest, Mr Ian and Pernet, Dr Cyril |
| Authors: | Pernet, C. R., McAleer, P., Latinus, M., Gorgolewski, K. J., Charest, I., Bestelmeyer, P. E.G., Watson, R. H., Fleming, D., Crabbe, F., Valdes-Sosa, M., and Belin, P. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience College of Science and Engineering > School of Psychology |
| Journal Name: | NeuroImage |
| Publisher: | Elsevier B.V. |
| ISSN: | 1053-8119 |
| ISSN (Online): | 1095-9572 |
| Copyright Holders: | Copyright © 2015 The Authors |
| First Published: | First published in NeuroImage 119:164-174 |
| Publisher Policy: | Reproduced under a Creative Commons License |
| Related URLs: |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric