Smith, C. J., Fisher, M. and McKay, G. A. (2010) Drugs for diabetes: part 2 sulphonylureas. British Journal of Cardiology, 17(6), pp. 279-282.
Full text not currently available from Enlighten.
Publisher's URL: http://bjcardio.co.uk/2010/11/drugs-for-diabetes-part-2-sulphonylureas/
Abstract
Sulphonylureas are well established in the treatment of type 2 diabetes mellitus. They are effective in improving glycaemic control and preventing microvascular complications. Side effects that can restrict use include hypoglycaemia and weight gain. Although there is no clear evidence for reduction of cardiovascular disease from randomised-controlled trials, follow-up data from the United Kingdom Prospective Diabetes Study (UKPDS) shows reduced cardiovascular risk. Concerns about sulphonylureas causing inhibition of ischaemic preconditioning are relevant in primary angioplasty, but there is a lack of clear evidence, with a need for randomised-controlled trials to investigate this further.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | McKay, Dr Gerard and Smith, Dr Christopher |
| Authors: | Smith, C. J., Fisher, M., and McKay, G. A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | British Journal of Cardiology |
| Journal Abbr.: | Br J Cardiol |
| Publisher: | MediNews Limited |
| ISSN: | 0969-6113 |
| ISSN (Online): | 1753-4313 |
University Staff: Request a correction | Enlighten Editors: Update this record
Deposit and Record Details
Deposit and Record Details