Hypertension in pregnancy: a review of therapeutic options

Kernaghan, D., Duncan, A.C. and McKay, G.A. (2012) Hypertension in pregnancy: a review of therapeutic options. Obstetric Medicine, 5(2), pp. 44-49. (doi: 10.1258/om.2011.110061)

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Abstract

Hypertensive disorders in pregnancy are common and can occur as a result of pre-existing hypertension or as new onset hypertension usually in the second half of pregnancy. In either situation there is potential for considerable perinatal and maternal morbidity and mortality. This review article aims to compare therapeutic options outlined in a selection of national guidelines and to look in more detail at the most commonly prescribed drugs – labetalol, methyldopa and nifedipine – with respect to their pharmacology and the evidence for their use in pregnancy. We will also consider the rationale for identifying and treating hypertension in pregnancy and the effect this can have on short- and long-term maternal and neonatal outcomes.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McKay, Dr Gerard
Authors: Kernaghan, D., Duncan, A.C., and McKay, G.A.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Obstetric Medicine
Publisher:SAGE Publications
ISSN:1753-495X
ISSN (Online):1753-4968

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