Calder, E. D.D. and Sutherland, A. (2015) Enantioselective synthesis of 3-methyleneindan-1-ols via a one-pot allylboration–Heck reaction of 2-bromobenzaldehydes. Organic Letters, 17(10), pp. 2514-2517. (doi: 10.1021/acs.orglett.5b01047) (PMID:25933177)
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Abstract
A novel, one-pot allylboration–Heck reaction of 2-bromobenzaldehydes has been developed for the general and efficient synthesis of 3-methyleneindan-1-ols. Modification of the one-pot procedure to include chiral Brønsted acid catalyzed allylation has allowed the preparation of these building blocks in high enantioselectivity and excellent yields.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Sutherland, Professor Andrew |
Authors: | Calder, E. D.D., and Sutherland, A. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Organic Letters |
Journal Abbr.: | Org. Lett. |
Publisher: | American Chemical Society |
ISSN: | 1523-7060 |
ISSN (Online): | 1523-7052 |
Copyright Holders: | Copyright © 2015 The Authors |
First Published: | First published in Organic Letters 17(10):2514-2517 |
Publisher Policy: | Reproduced under a Creative Commons License |
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