Hanratty, J., Changez, H., Smith, A. and Wales, C. (2015) Panton-valentine leukocidin positive staphylococcal aureus infections of the head and neck: case series and brief review of literature. Journal of Oral and Maxillofacial Surgery, 73(4), pp. 666-670. (doi: 10.1016/j.joms.2014.10.004) (PMID:25544295)
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Abstract
Panton-valentine leukocidin (PVL) is a pore-forming cytotoxin produced by some clones of Staphylococcus aureus that is associated with infections ranging from uncomplicated skin and soft tissue infections to life-threatening necrotizing pneumonia. PVL S aureus–associated maxillofacial infections are rarely reported; therefore, a high degree of clinical suspicion is warranted and close liaison with microbiologists and appropriate samples are required for optimal management. This report discusses the management and learning points from 3 such cases managed by the Greater Glasgow and Clyde National Health Service maxillofacial surgical teams.<p></p> Panton-Valentine leukocidin (PVL) is a virulence factor produced by some clones of Staphylococcus aureus. These isolates are associated with infections that range from uncomplicated skin and soft tissue infections to life-threatening entities such as necrotizing pneumonia. 1 and 2 This report presents a case series of 3 PVL-positive community-acquired methicillin-sensitive S aureus (PVL CA-MSSA) infections treated by the maxillofacial team at the Southern General Hospital (Glasgow, United Kingdom) over a 6-month period in 2013 and discusses the clinical implications of PVL S aureus infections in this patient group.<p></p>
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Smith, Professor Andrew |
Authors: | Hanratty, J., Changez, H., Smith, A., and Wales, C. |
College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School |
Journal Name: | Journal of Oral and Maxillofacial Surgery |
Publisher: | Elsevier |
ISSN: | 0278-2391 |
ISSN (Online): | 1531-5053 |
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