cGMP signalling in a transporting epithelium

Davies, S.-A. and Day, J.P. (2006) cGMP signalling in a transporting epithelium. Biochemical Society Transactions, 34, pp. 512-514. (doi: 10.1042/BST0340512) (PMID:16856847)

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The biochemical aspects of cGMP signalling are well known, although in vivo roles of cGMP have only been recently discovered through work in genetic model organisms. The Drosophila melanogaster Malpighian (renal) tubule has been used to address the roles of cGMP in epithelial function. Here, we describe some of this work and outline recent progress in understanding the organotypic function of novel phosphodiesterases encoded by the D. melanogaster genome.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Davies, Professor Shireen
Authors: Davies, S.-A., and Day, J.P.
College/School:College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
Journal Name:Biochemical Society Transactions
ISSN (Online):1470-8752

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
378481Exploration of cyclic 3', 5' guanosine monophosphate (cGMP) signalling dynamics in vivoShireen DaviesBiotechnology and Biological Sciences Research Council (BBSRC)BB/C000633/1Institute of Molecular Cell and Systems Biology