Advances in urinary proteome analysis and applications in systems biology

Filip, S., Zoidakis, J., Vlahou, A. and Mischak, H. (2014) Advances in urinary proteome analysis and applications in systems biology. Bioanalysis, 6(19), pp. 2549-2569. (doi: 10.4155/bio.14.210)

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The urinary proteome is the focus of many studies due to the ease of urine collection and the relative proteome stability. Systems biology allows the combination of multiple omics studies, forming a link between proteomics, metabolomics, genomics and transcriptomics. In-depth data interpretation is achieved by bioinformatics analysis of -omics data sets. It is expected that the contribution of systems biology to the study of the urinary proteome will offer novel insights. The main focus of this review is on technical aspects of proteomics studies, available tools for systems biology analysis and the application of urinary proteomics in clinical studies and systems biology.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Mischak, Professor Harald
Authors: Filip, S., Zoidakis, J., Vlahou, A., and Mischak, H.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:Bioanalysis
Publisher:Future Science

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
593511SysVascChristian DellesEuropean Commission (EC)603288RI CARDIOVASCULAR & MEDICAL SCIENCES