Regoes, R. R., Yates, A. and Antia, R. (2007) Mathematical models of cytotoxic T-lymphocyte killing. Immunology and Cell Biology, 85(4), pp. 274-279. (doi: 10.1038/sj.icb.7100053)
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Publisher's URL: http://dx.doi.org/10.1038/sj.icb.7100053
Abstract
By killing infected host cells, cytotoxic T lymphocytes (CTL) mediate an important defense mechanism against viruses and other intracellular pathogens. Quantitative aspects of this killing process have been studied for several decades in vitro. More recently, methods have been developed to measure the timescales of CTL killing in vivo. Here, we review the estimates of kinetic rates involved in CTL killing which were obtained in these studies, and elaborate on the differences between them.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Yates, Professor Andrew |
| Authors: | Regoes, R. R., Yates, A., and Antia, R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Immunology and Cell Biology |
| Publisher: | Australasian Society for Immunology |
| ISSN: | 0818-9641 |
| ISSN (Online): | 1440-1711 |
| Related URLs: |
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