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Hartley, R. et al. (2019) Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology and Medicine, (Accepted for Publication)

Pinho, B. R., Reis, S. D., Hartley, R. C. , Murphy, M. P. and Oliveira, J. M.A. (2019) Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Free Radical Biology and Medicine, 130, pp. 318-327. (doi:10.1016/j.freeradbiomed.2018.10.446) (PMID:30389496) (PMCID:PMC6340810)

Murphy, M. P. and Hartley, R. C. (2018) Mitochondria as a therapeutic target for common pathologies. Nature Reviews Drug Discovery, (doi:10.1038/nrd.2018.174) (PMID:30393373) (Early Online Publication)

Fazakerley, D. J. et al. (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. Journal of Biological Chemistry, 293(19), pp. 7315-7328. (doi:10.1074/jbc.RA117.001254) (PMID:29599292) (PMCID:PMC5950018)

Mills, E. L. et al. (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 5556, pp. 113-117. (doi:10.1038/nature25986) (PMID:29590092)

Cao, Z., Mitchell, L., Hsia, O., Scarpa, M., Caldwell, S. T., Alfred, A. D., Gennaris, A., Collet, J.-F., Hartley, R. C. and Bulleid, N. J. (2018) Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase. Biochemical Journal, 475, pp. 827-838. (doi:10.1042/BCJ20170929) (PMID:29420254)

Booty, L. M. et al. (2018) Selective disruption of mitochondrial thiol redox state in cells and in vivo. Cell Chemical Biology, (Accepted for Publication)

Shchepinova, M. M. et al. (2017) MitoNeoD: a mitochondria-targeted superoxide probe. Cell Chemical Biology, 24(10), 1285-1298.e12. (doi:10.1016/j.chembiol.2017.08.003) (PMID:28890317)

Arndt, S. et al. (2017) Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA. Journal of Biological Chemistry, 292(19), pp. 7761-7773. (doi:10.1074/jbc.M117.784678) (PMID:28320864) (PMCID:PMC5427258)

This list was generated on Mon Feb 18 05:57:14 2019 GMT.